WDR5 Antibody
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P61964
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the WDR5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This WDR5 antibody is available for research use only.
Storage Conditions
Aliquot the WDR5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the WDR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Drosophila, Rat
Image Legend
Western blot analysis of lysate from 1) human HeLa and 2) mouse NIH3T3 cell line using WDR5 antibody at 1:1000. Predicted molecular weight ~36 kDa.
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