Histone H3 Antibody
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P68431
Host
Rabbit
Reactivity
Mouse
Immunogen
This Histone H3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 8~39 amino acids from human.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Histone H3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Histone H3 antibody is available for research use only.
Storage Conditions
Aliquot the Histone H3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Histone H3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Rat
Image Legend
Western blot analysis of lysate from mouse C2C12 cell line using Histone H3 antibody diluted at 1:1000.
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