OPA1 Antibody
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O60313
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the OPA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This OPA1 antibody is available for research use only.
Storage Conditions
Aliquot the OPA1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the OPA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Chicken, Zebrafish
Image Legend
Western blot analysis of lysate from (1) HeLa cell line, (2) mouse brain and (3) rat brain tissue lysate using OPA1 antibody at 1:1000.
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