HSP90 Antibody / HSP90AA1
Heat Shock Protein 90 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P07900
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids from 150-400 of the human protein were used as the immunogen for this HSP90AA1 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
803CT9.1.2
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the HSP90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HSP90 antibody is available for research use only.
Storage Conditions
Aliquot the HSP90 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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