HSP-90 Antibody / HSP90AA1

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P07900

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This HSP-90 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 644-677 amino acids from the C-terminal region of human HSP90AA1.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Store at 4oC for up to one month. For long term, aliquot the HSP-90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HSP-90 antibody is available for research use only.

Storage Conditions

Store at 4°C for up to one month. For long term, aliquot the HSP-90 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the HSP-90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine, Chicken, Hamster, Pig, Rabbit, Zebrafish

Image Legend

Western blot analysis of lysate from A431, A549, HeLa, SK-N-MC, mouse NIH3T3, rat PC-12 cell line using HSP-90 antibody diluted at 1:1000 for each lane.