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HSP90 Antibody / HSP90AA1

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P07900

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This HSP90 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 299-331 amino acids from the Central region of human HSP90AA1.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the HSP90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HSP90 antibody is available for research use only.

Storage Conditions

Aliquot the HSP90 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine, Chicken, Hamster, Pig, Rabbit, Rat, Zebrafish

Image Legend

Western blot analysis of lysate from A431, A549, HeLa, SK-N-MC, mouse NIH3T3 cell line using HSP90 antibody diluted at 1:1000 for each lane.

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