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HSP90 Antibody / HSP90AA1

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P07900

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This HSP90 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 57-89 amino acids from the N-terminal region of human HSP90AA1.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the HSP90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HSP90 antibody is available for research use only.

Storage Conditions

Aliquot the HSP90 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine, Chicken, Drosophila, Hamster, Pig, Rabbit, Zebrafish

Image Legend

Western blot analysis of lysate from A431, A549, HeLa, SK-N-MC, mouse NIH3T3, rat PC-12 cell line using HSP90 antibody at 1:1000.

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