CREB1 Antibody

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P16220

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

This CREB1 antibody was produced from a mouse immunized with a recombinant protein from human CREB1.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

1335CT115.203.189

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CREB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CREB1 antibody is available for research use only.

Storage Conditions

Aliquot the CREB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the CREB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of lysate from 1) human A549, 2) mouse Neuro-2a, 3) mouse NIH3T3, and 4) rat C6 cell line using CREB1 antibody at 1:1000. Predicted molecular weight is 37 kDa but routinely observed at ~43 kDa.