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CD74 Antibody

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow Cytometry: 1:25, Western blot: 1:1000

UniProt

P04233

Host

Mouse

Reactivity

Human

Immunogen

This CD74 antibody was produced from a mouse immunized with a KLH conjugated synthetic peptide between 1-232 amino acids from human protein.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

1267CT820.116.140.154

Applications

WB, FACS, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CD74 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CD74 antibody is available for research use only.

Storage Conditions

Aliquot the CD74 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.nsjbio.com/tds-pdf/cd74-antibody-1267ct820116140154-f52443

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the CD74 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Flow cytometric analysis of Raji cells using CD74 antibody (green) and an isotype control of mouse IgG2b (blue) ; Ab was diluted at 1:25 dilution.

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