CD74 Antibody
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow Cytometry: 1:25, Western blot: 1:1000
UniProt
P04233
Host
Mouse
Reactivity
Human
Immunogen
This CD74 antibody was produced from a mouse immunized with a KLH conjugated synthetic peptide between 1-232 amino acids from human protein.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
1267CT820.116.140.154
Applications
WB, FACS, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CD74 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD74 antibody is available for research use only.
Storage Conditions
Aliquot the CD74 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CD74 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Flow cytometric analysis of Raji cells using CD74 antibody (green) and an isotype control of mouse IgG2b (blue) ; Ab was diluted at 1:25 dilution.
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