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UCH37 Antibody

Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q9Y5K5

Host

Mouse

Reactivity

Human

Immunogen

Purified His-tagged protein was used to produced this monoclonal UCH37 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

854CT5.5.6

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the UCH37 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This UCH37 antibody is available for research use only.

Storage Conditions

Aliquot the UCH37 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the UCH37 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

UCH37 antibody western blot analysis in 293, HeLa, 293T lysate. Predicted molecular weight ~37 kDa (4 isoforms) .

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