ACE2 Antibody

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q9BYF1

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Purified His-tagged protein was used to produced this monoclonal ACE2 antibody.

Clonality

Monoclonal

Isotype

IgM k

Clone

881CT16.4.4

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ACE2 antibody is available for research use only.

Storage Conditions

Aliquot the ACE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

ACE2 antibody western blot analysis in (1) 293, (2) K562, (3) MCF-7, (4) SK-BR-3, (5) T47D, (6) MDA-MB-453 cell line and (7) mouse testis tissue lysate. Predicted molecular weight: 90-100 kDa.