TBP Antibody / TATA-box-binding protein
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Product Specifications
CAS Number
9007-83-4
Specifications
IHC (Paraffin) : 1:25, Western blot: 1:1000-2:000
UniProt
P20226
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Purified His-tagged protein was used to produced this monoclonal TBP antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
830CT4.3.3
Applications
IHC-P, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TBP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TBP antibody is available for research use only.
Storage Conditions
Aliquot the TBP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/tbp-antibody-tata-box-binding-protein-830ct433-f52225
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TBP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear
Image Legend
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