SUZ12 Antibody / Suppressor of zeste 12 protein homolog
Selected Variant
F52128-0.08ML
Size: 0.08 mL
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q15022
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 559-588 from the human protein was used as the immunogen for this SUZ12 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SUZ12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SUZ12 antibody is available for research use only.
Storage Conditions
Aliquot the SUZ12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SUZ12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
SUZ12 antibody western blot analysis in human Ramos cell lysate. Observed molecular weight 83~95 kDa.
Price
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