Histone H3 Antibody
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P68431
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 28-57 from the human protein was used as the immunogen for this Histone H3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Histone H3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Histone H3 antibody is available for research use only.
Storage Conditions
Aliquot the Histone H3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Histone H3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, C. elegans, Chicken, Drosophila, Mouse, Pig, Rat, Xenopus, Zebrafish
Image Legend
Histone H3 antibody western blot analysis in HeLa lysate.
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