Anti-Bcl-2 Antibody
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P10415
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 49-76 from the human protein was used as the immunogen for this anti-Bcl-2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the anti-Bcl-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This anti-Bcl-2 antibody is available for research use only.
Storage Conditions
Aliquot the anti-Bcl-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the anti-Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Anti-Bcl-2 antibody western blot analysis in HeLa lysate
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