Src Antibody
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000, IHC (Paraffin) : 1:50, Flow Cytometry: 1:50, Immunofluorescence: 1:50
UniProt
P12931
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 24-52 from the human protein was used as the immunogen for this Src antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, IF, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Src antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Src antibody is available for research use only.
Storage Conditions
Aliquot the Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
Src antibody western blot analysis in (1) MCF-7 and (2) A431 lysate
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