CFP Antibody / Complement Factor P / Properdin
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
P27918
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CFP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CFP antibody is available for research use only.
Storage Conditions
Aliquot the CFP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CFP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of CFP antibody and CEM lysate.
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
