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DKK-1 Antibody

DKK-1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

O94907

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 58-84 from the human protein was used as the immunogen for this DKK-1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the DKK-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This DKK-1 antibody is available for research use only.

Storage Conditions

Aliquot the DKK-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the DKK-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of DKK-1 antibody and T47D lysate. Predicted molecular weight: 26-40 kDa depending on glycosylation level.

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