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PTPRD Antibody

PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P23468

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 343-371 from the human protein was used as the immunogen for this PTPRD antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PTPRD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PTPRD antibody is available for research use only.

Storage Conditions

Aliquot the PTPRD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PTPRD antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of PTPRD antibody and HeLa lysate.

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