NAMPT Antibody
NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
P43490
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 400-426 from the human protein was used as the immunogen for this NAMPT antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the NAMPT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NAMPT antibody is available for research use only.
Storage Conditions
Aliquot the NAMPT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NAMPT antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat, Pig
Location
Predominantly cytoplasmic, some nuclear staining may also be seen
Image Legend
IHC analysis of FFPE human skeletal muscle stained with NAMPT antibody. Expected molecular weight ~56 kDa.
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