C5 Antibody
C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunohistochemistry (Paraffin) : 1:50-1:100, Flow cytometry: 1:10-1:50
UniProt
P01031
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 253-281 from the human protein was used as the immunogen for this C5 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, FACS, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the C5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This C5 antibody is available for research use only.
Storage Conditions
Aliquot the C5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the C5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of C5 antibody and HL-60 lysate
Documents
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