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MyD88 Antibody

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50

UniProt

Q99836

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, FACS, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MyD88 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MyD88 antibody is available for research use only.

Storage Conditions

Aliquot the MyD88 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Primate

Image Legend

IHC analysis of FFPE human lung carcinoma stained with MyD88 antibody

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