MyD88 Antibody
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
Q99836
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MyD88 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MyD88 antibody is available for research use only.
Storage Conditions
Aliquot the MyD88 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Primate
Image Legend
IHC analysis of FFPE human lung carcinoma stained with MyD88 antibody
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