TRPM8 Antibody
TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
Q7Z2W7
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 521-552 from the human protein was used as the immunogen for this TRPM8 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TRPM8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TRPM8 antibody is available for research use only.
Storage Conditions
Aliquot the TRPM8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TRPM8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of lysate from human brain tissue using TRPM8 antibody at 1:1000. Predicted molecular weight ~128 kDa.
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