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P70S6Kb Antibody

RPS6KB2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [Wiki]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q9UBS0

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A portion of amino acids 243-272 from the human protein was used as the immunogen for this p70S6Kb antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the p70S6Kb antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This p70S6Kb antibody is available for research use only.

Storage Conditions

Aliquot the p70S6Kb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the p70S6Kb antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of p70S6Kb antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the human RPS6KB2 gene (2) . Predicted molecular weight: 60-70 kDa
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