PAK2 Antibody
PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q13177
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 192-222 from the human protein was used as the immunogen for this PAK2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PAK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PAK2 antibody is available for research use only.
Storage Conditions
Aliquot the PAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of ovary lysate with PAK2 antibody.
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