MERTK Antibody
MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin) : 1:50-1:10, Flow Cytometry: 1:10-1:50
UniProt
Q12866
Host
Rabbit
Reactivity
Human
Immunogen
This MERTK antibody was produced from rabbits immunized with a his tag recombinant protein of human MERTK.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, FACS, IF, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MERTK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MERTK antibody is available for research use only.
Storage Conditions
Aliquot the MERTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MERTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Fluorescent image of U251 cell stained with MERTK antibody at 1:25. MERTK immunoreactivity is localized to vesicles.
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