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MERTK Antibody

MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin) : 1:50-1:10, Flow Cytometry: 1:10-1:50

UniProt

Q12866

Host

Rabbit

Reactivity

Human

Immunogen

This MERTK antibody was produced from rabbits immunized with a his tag recombinant protein of human MERTK.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC, FACS, IF, WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MERTK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MERTK antibody is available for research use only.

Storage Conditions

Aliquot the MERTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the MERTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Fluorescent image of U251 cell stained with MERTK antibody at 1:25. MERTK immunoreactivity is localized to vesicles.

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