Acetylcholinesterase Antibody / ACHE
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunohistochemistry (FFPE) : 1:10-1:50, Flow cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
P22303
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 147-175 from the human protein was used as the immunogen for this Acetylcholinesterase antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, FACS, IF, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Acetylcholinesterase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Acetylcholinesterase antibody is available for research use only.
Storage Conditions
Aliquot the Acetylcholinesterase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Acetylcholinesterase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Guinea pig
Location
Cytoplasmic, membranous
Image Legend
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