B-RAF Antibody
BRAF is a human gene, with the protein more formally known as serine/threonine-protein kinase B-Raf. The protein is involved in sending signals inside cells, which are involved in directing cell growth. Drugs that treat cancers driven by BRAF mutations have been developed. Two of these drugs, Vemurafenib and Dabrafenib are approved by FDA for treatment of late-stage melanoma. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:10-1:50, Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
P15056
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 424-453 from the human protein was used as the immunogen for this B-RAF antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IHC, IF, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Store at 4oC for up to one month. For long term, aliquot the B-RAF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This B-RAF antibody is available for research use only.
Storage Conditions
Store at 4°C for up to one month. For long term, aliquot the B-RAF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Prediction Reactivity
Mouse, Chicken
Image Legend
Fluorescent image of C2C12 cell stained with B-RAF antibody at 1:25. Immunoreactivity is localized to the cytoplasm.
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