ALK1 Antibody / ACVRL1
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow Cytometry: 1:10-1:50, IHC (Paraffin) : 1:50-1:100, Western blot: 1:1000
UniProt
P37023
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 38-68 from the human protein was used as the immunogen for this ALK1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ALK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ALK1 antibody is available for research use only.
Storage Conditions
Aliquot the ALK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ALK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot of ALK1 antibody and mouse heart tissue lysate. Predicted molecular weight ~60 kDa.
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