BACE1 Antibody
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [UniProt]
Product Specifications
UniProt
P56817
Host
Rabbit
Immunogen
A portion of amino acids 38-70 from the human protein was used as the immunogen for this BACE1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Store at 4oC for up to one month. For long term, aliquot the BACE1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This BACE1 antibody is available for research use only.
CAS Number
9007-83-4
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