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C-Abl Antibody

ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50

UniProt

P00519

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 741-769 from the human protein was used as the immunogen for this c-Abl antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, IF, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the c-Abl antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This c-Abl antibody is available for research use only.

Storage Conditions

Aliquot the c-Abl antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the c-Abl antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC analysis of FFPE human hepatocarcinoma tissue stained with c-Abl antibody

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