PDGFRL Antibody
PDGFRL (Platelet-derived growth factor receptor-like protein) bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q15198
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 328-357 from the human protein was used as the immunogen for this PDGFRL antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PDGFRL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PDGFRL antibody is available for research use only.
Storage Conditions
Aliquot the PDGFRL antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PDGFRL antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC analysis of FFPE human colon carcinoma stained with PDGFRL antibody
Frequently Asked Questions
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