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PDGFRL Antibody

PDGFRL (Platelet-derived growth factor receptor-like protein) bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100

UniProt

Q15198

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 328-357 from the human protein was used as the immunogen for this PDGFRL antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PDGFRL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PDGFRL antibody is available for research use only.

Storage Conditions

Aliquot the PDGFRL antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PDGFRL antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC analysis of FFPE human colon carcinoma stained with PDGFRL antibody

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