MUSK Antibody
MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Product Specifications
CAS Number
9007-83-4
UniProt
O15146
Host
Rabbit
Immunogen
This MUSK antibody was produced from rabbits immunized with human MUSK recombinant protein.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IF, ELISA
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the MUSK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MUSK antibody is available for research use only.
Frequently Asked Questions
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