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Integrin linked kinase Antibody

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK encodes a predicted 451-amino acid protein, with an apparent molecular weight of 59 kD. The ILK protein is a serine/threonine protein kinase with 4 ankyrin-like repeats. ILK regulates integrin-mediated signal transduction.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100

UniProt

O55222

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 11-41 from the mouse protein was used as the immunogen for this Integrin linked kinase antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Integrin linked kinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Integrin linked kinase antibody is available for research use only.

Storage Conditions

Aliquot the Integrin linked kinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Integrin linked kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine, Rat

Location

Cytoplasmic

Image Legend

Western blot analysis of Integrin linked kinase antibody and HL-60 cell lysate. Expected molecular weight: 51-59 kDa.

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