Integrin linked kinase Antibody
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK encodes a predicted 451-amino acid protein, with an apparent molecular weight of 59 kD. The ILK protein is a serine/threonine protein kinase with 4 ankyrin-like repeats. ILK regulates integrin-mediated signal transduction.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
O55222
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 11-41 from the mouse protein was used as the immunogen for this Integrin linked kinase antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Integrin linked kinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Integrin linked kinase antibody is available for research use only.
Storage Conditions
Aliquot the Integrin linked kinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Integrin linked kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Rat
Location
Cytoplasmic
Image Legend
Western blot analysis of Integrin linked kinase antibody and HL-60 cell lysate. Expected molecular weight: 51-59 kDa.
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