HER2 Antibody (ERBB2, NEU)
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Product Specifications
CAS Number
9007-83-4
UniProt
P04626
Host
Rabbit
Immunogen
This HER2 antibody was produced from rabbits immunized with human recombinant ErbB2 protein.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, IF, ELISA
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the HER2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HER2 antibody is available for research use only.
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