CSF1R Antibody
CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. This protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50, IHC (Paraffin) : 1:10-1:50
UniProt
P07333
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 940-971 from the human protein was used as the immunogen for this CSF1R antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CSF1R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CSF1R antibody is available for research use only.
Storage Conditions
Aliquot the CSF1R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CSF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC analysis of FFPE human lung carcinoma tissue stained with CSF1R antibody
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