ACO2 Antibody / Aconitase 2
Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1000, IHC (Paraffin) : 1:10-1:50
UniProt
Q99798
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 294-325 from the human protein was used as the immunogen for this ACO2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ACO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ACO2 antibody is available for research use only.
Storage Conditions
Aliquot the ACO2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ACO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, granular
Image Legend
Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with ACO2 antibody at 1:1000. Predicted molecular weight ~85 kDa.
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