ACAT1 Antibody
Acetyl-CoA acetyltransferase 1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in the gene encoding ACAT1 are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
P24752
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 296-329 from the human protein was used as the immunogen for this ACAT1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ACAT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ACAT1 antibody is available for research use only.
Storage Conditions
Aliquot the ACAT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ACAT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Primate
Location
Cytoplasmic
Image Legend
Western blot testing of ACAT1 antibody at 1:2000 dilution. Lane 1: human SW620 lysate; 2: mouse liver lysate; Predicted molecular weight: ~45kDa.
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
