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NQO1 Antibody

NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50

UniProt

P15559

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 118-144 from the human protein was used as the immunogen for this NQO1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS, IF, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NQO1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NQO1 antibody is available for research use only.

Storage Conditions

Aliquot the NQO1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the NQO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of NQO1 antibody and NCI-H460 lysate. Predicted molecular weight ~30kDa.

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