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Ceruloplasmin Antibody

Ceruloplasmin (CP) is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II) transferrin to Fe (III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, Flow Cytometry: 1:10-1:50

UniProt

P00450

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 121-151 from the human protein was used as the immunogen for this Ceruloplasmin antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

FACS, WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Ceruloplasmin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Ceruloplasmin antibody is available for research use only.

Storage Conditions

Aliquot the Ceruloplasmin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Ceruloplasmin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Ceruloplasmin antibody western blot analysis in human blood plasma lysate. Predicted molecular weight ~130 kDa.

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