Anti-PCSK9 Antibody

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:100, Flow Cytometry: 1:10-1:50

UniProt

Q8NBP7

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 479-508 from the human protein was used as the immunogen for this anti-PCSK9 antibody.

Clonality

Polyclonal

Isotype

Applications

IHC, FACS, WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Store at 4oC for up to one month. For long term, aliquot the anti-PCSK9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This anti-PCSK9 antibody is available for research use only.

Storage Conditions

Store at 4°C for up to one month. For long term, aliquot the anti-PCSK9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the anti-PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.