PCSK9 Antibody
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow Cytometry: 1:25, IHC (Paraffin) : 1:25, Western blot: 1:1000
UniProt
Q8NBP7
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 144-173 from the human protein was used as the immunogen for this PCSK9 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IHC, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PCSK9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PCSK9 antibody is available for research use only.
Storage Conditions
Aliquot the PCSK9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of lysate from HeLa cell line using PCSK9 antibody. Predicted size: Pro/mature ~74/64 kDa
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