Aromatase Antibody / CYP19A1
CYP19A1/Aromatase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P11511
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 221-253 from the human protein was used as the immunogen for this Aromatase antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Aromatase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Aromatase antibody is available for research use only.
Storage Conditions
Aliquot the Aromatase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Aromatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rabbit
Image Legend
Western blot analysis of CYP19A1 / Aromatase antibody and HL-60 lysate. Predicted molecular weight ~58 kDa.
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