HMGB2 Antibody
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D) J recombination.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P26583
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 92-118 from the human protein was used as the immunogen for this HMGB2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the HMGB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HMGB2 antibody is available for research use only.
Storage Conditions
Aliquot the HMGB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the HMGB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat, Bovine, Pig
Image Legend
HMGB2 antibody western blot analysis in (1) HL-60, (2) K562, (3) H-4-II-E lysate. Expected molecular weight ~24 kDa.
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