PDK4 Antibody
PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:100, Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
Q16654
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 382-410 from the human protein was used as the immunogen for this PDK4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PDK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PDK4 antibody is available for research use only.
Storage Conditions
Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot of PDK4 antibody and mouse skeletal muscle tissue lysate. Predicted molecular weight ~46 kDa
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