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PDK4 Antibody

PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1:100, Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50

UniProt

Q16654

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 382-410 from the human protein was used as the immunogen for this PDK4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IF, WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PDK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PDK4 antibody is available for research use only.

Storage Conditions

Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot of PDK4 antibody and mouse skeletal muscle tissue lysate. Predicted molecular weight ~46 kDa

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