Aurora-C Antibody
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Product Specifications
UniProt
Q9UQB9
Host
Rabbit
Immunogen
A portion of amino acids 115-145 from the human protein was used as the immunogen for this Aurora-C antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Aurora-C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Aurora-C antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6681672/datasheet/f50014-0.4ml.pdf
CAS Number
9007-83-4
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