CD11c Antibody / ITGAX
ITGAX is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4) . The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
P20702
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1119-1145 from the human protein was used as the immunogen for this CD11c antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IF, WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CD11c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD11c antibody is available for research use only.
Storage Conditions
Aliquot the CD11c antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CD11c antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cell surface, cytoplasmic
Image Legend
Western blot analysis of CD11c antibody and MDA-MB231 lysate. Predicted molecular weight: 128~150 kDa.
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