PAX-6 Antibody
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity) . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
P26367
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 352-380 from the human protein was used as the immunogen for this PAX-6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, IF, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PAX-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PAX-6 antibody is available for research use only.
Storage Conditions
Aliquot the PAX-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PAX-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear, cytoplasmic
Image Legend
Western blot analysis of PAX-6 in Y79 lysate. Predicted molecular weight ~48kDa.
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